| 25 Sept 2021 | ND 183 v SV 187/7Final · List A | Southern Vipers won by 3 wickets | Northampton | Rachael Heyhoe Flint Trophy 2021 |
| 22 Sept 2021 | CS 175/7 v ND 176/4Match · List A | Northern Diamonds won by 6 wickets | Scarborough | Rachael Heyhoe Flint Trophy 2021 |
| 18 Sept 2021 | LIG 320/6 v CS 296/9Match · List A | Lightning won by 24 runs | Loughborough | Rachael Heyhoe Flint Trophy 2021 |
| 18 Sept 2021 | THU 185 v SES 130Match · List A | Thunder won by 55 runs | Beckenham | Rachael Heyhoe Flint Trophy 2021 |
| 18 Sept 2021 | WS 313/4 v SUN 277Match · List A | Western Storm won by 36 runs | Bristol | Rachael Heyhoe Flint Trophy 2021 |
| 18 Sept 2021 | ND 256 v SV 260/5Match · List A | Southern Vipers won by 5 wickets | Southampton | Rachael Heyhoe Flint Trophy 2021 |
| 12 Sept 2021 | ND 294/6 v THU 189/8Match · List A | Northern Diamonds won by 105 runs | Chester-le-Street | Rachael Heyhoe Flint Trophy 2021 |
| 12 Sept 2021 | CS 229 v SES 114Match · List A | Central Sparks won by 115 runs | Worcester | Rachael Heyhoe Flint Trophy 2021 |
| 12 Sept 2021 | WS 228/7 v LIG 166Match · List A | Western Storm won by 62 runs | Bristol | Rachael Heyhoe Flint Trophy 2021 |
| 12 Sept 2021 | SV 309/9 v SUN 308/6Match · List A | Southern Vipers won by 1 run | Chelmsford | Rachael Heyhoe Flint Trophy 2021 |
| 10 Sept 2021 | WS 183 v ND 184/3Match · List A | Northern Diamonds won by 7 wickets | Chester-le-Street | Rachael Heyhoe Flint Trophy 2021 |
| 10 Sept 2021 | SES 293/9 v LIG 265Match · List A | South East Stars won by 28 runs | Beckenham | Rachael Heyhoe Flint Trophy 2021 |
| 10 Sept 2021 | SUN 204/7 v CS 208/4Match · List A | Central Sparks won by 6 wickets (DLS method) | Northwood | Rachael Heyhoe Flint Trophy 2021 |
| 10 Sept 2021 | THU 110 v SV 112/7Match · List A | Southern Vipers won by 3 wickets | Sale | Rachael Heyhoe Flint Trophy 2021 |
| 12 Jun 2021 | SES 250/6 v ND 254/7Match · List A | Northern Diamonds won by 3 wickets | Leeds | Rachael Heyhoe Flint Trophy 2021 |
| 12 Jun 2021 | SUN 206/9 v LIG 210/5Match · List A | Lightning won by 5 wickets | Loughborough | Rachael Heyhoe Flint Trophy 2021 |
| 12 Jun 2021 | CS 203 v THU 205/8Match · List A | Thunder won by 2 wickets | Worcester | Rachael Heyhoe Flint Trophy 2021 |
| 12 Jun 2021 | WS 177 v SV 178/2Match · List A | Southern Vipers won by 8 wickets | Taunton | Rachael Heyhoe Flint Trophy 2021 |
| 6 Jun 2021 | LIG 259/5 v THU 125Match · List A | Lightning won by 134 runs | Chester | Rachael Heyhoe Flint Trophy 2021 |
| 5 Jun 2021 | WS 245/8 v SES 249/4Match · List A | South East Stars won by 6 wickets | London | Rachael Heyhoe Flint Trophy 2021 |
| 5 Jun 2021 | SUN 53 v ND 54/1Match · List A | Northern Diamonds won by 9 wickets | Cambridge | Rachael Heyhoe Flint Trophy 2021 |
| 5 Jun 2021 | CS 224 v SV 104Match · List A | Central Sparks won by 120 runs | Brighton | Rachael Heyhoe Flint Trophy 2021 |
| 31 May 2021 | ND 151 v LIG 145Match · List A | Northern Diamonds won by 6 runs | Kibworth | Rachael Heyhoe Flint Trophy 2021 |
| 31 May 2021 | CS 295/7 v WS 254/9Match · List A | Central Sparks won by 41 runs | Birmingham | Rachael Heyhoe Flint Trophy 2021 |
| 31 May 2021 | SES 137 v SV 138/3Match · List A | Southern Vipers won by 7 wickets | Beckenham | Rachael Heyhoe Flint Trophy 2021 |
| 31 May 2021 | THU 247/9 v SUN 211Match · List A | Thunder won by 36 runs | Chester | Rachael Heyhoe Flint Trophy 2021 |
| 29 May 2021 | ND 279 v CS 283/8Match · List A | Central Sparks won by 2 wickets | Leeds | Rachael Heyhoe Flint Trophy 2021 |
| 29 May 2021 | THU 291/8 v WS 295/9Match · List A | Western Storm won by 1 wicket | Bristol | Rachael Heyhoe Flint Trophy 2021 |
| 29 May 2021 | SES 324/7 v SUN 189Match · List A | South East Stars won by 135 runs | Chelmsford | Rachael Heyhoe Flint Trophy 2021 |
| 29 May 2021 | LIG 214/9 v SV 215/6Match · List A | Southern Vipers won by 4 wickets | Southampton | Rachael Heyhoe Flint Trophy 2021 |
