| 19 Aug 2021 | GLA 296/9 v DUR 238Final · List A | Glamorgan won by 58 runs | Nottingham | Royal London One-Day Cup 2021 |
| 17 Aug 2021 | SUR 280/8 v DUR 281/5Semi-final · List A | Durham won by 5 wickets | Chester-le-Street | Royal London One-Day Cup 2021 |
| 16 Aug 2021 | ESS 289 v GLA 293/5Semi-final · List A | Glamorgan won by 5 wickets | Cardiff | Royal London One-Day Cup 2021 |
| 15 Aug 2021 | GLO 242/7 v SUR 246/5Quarter-Final · List A | Surrey won by 5 wickets | London | Royal London One-Day Cup 2021 |
| 14 Aug 2021 | ESS 317/7 v YOR 188Quarter-Final · List A | Essex won by 129 runs | Chelmsford | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | DER 215 v SUR 219/2Match · List A | Surrey won by 8 wickets | Derby | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | HAM 225/9 v DUR 228/1Match · List A | Durham won by 9 wickets | Chester-le-Street | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | YOR 230 v GLA 226/8Match · List A | Yorkshire won by 4 runs | Cardiff | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | KEN 218/9 v GLO 219/2Match · List A | Gloucestershire won by 8 wickets | Beckenham | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | LAN 250/6 v ESS 250/8Match · List A | Match tied | Manchester | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | LEI 271 v NOR 261/9Match · List A | Leicestershire won by 4 runs (DLS method) | Northampton | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | SUS 333/4 v MID 330/8Match · List A | Sussex won by 3 runs | Brighton | Royal London One-Day Cup 2021 |
| 12 Aug 2021 | SOM 287/8 v WAR 289/7Match · List A | Warwickshire won by 3 wickets | Birmingham | Royal London One-Day Cup 2021 |
| 10 Aug 2021 | ESS 321/8 v SUS 224Match · List A | Essex won by 97 runs | Chelmsford | Royal London One-Day Cup 2021 |
| 10 Aug 2021 | NOR 210 v NOT 211/8Match · List A | Nottinghamshire won by 2 wickets | Grantham | Royal London One-Day Cup 2021 |
| 10 Aug 2021 | SOM 326/7 v LEI 327/6Match · List A | Leicestershire won by 4 wickets | Taunton | Royal London One-Day Cup 2021 |
| 10 Aug 2021 | WAR 268/9 v SUR 269/3Match · List A | Surrey won by 7 wickets | London | Royal London One-Day Cup 2021 |
| 10 Aug 2021 | DUR 289/9 v WOR 243Match · List A | Durham won by 46 runs | Worcester | Royal London One-Day Cup 2021 |
| 8 Aug 2021 | DER 108/6 v YOR 109/2Match · List A | Yorkshire won by 8 wickets | Chesterfield | Royal London One-Day Cup 2021 |
| 8 Aug 2021 | ESS 227/6 v DUR 233/8Match · List A | Durham won by 2 wickets (DLS method) | Chester-le-Street | Royal London One-Day Cup 2021 |
| 8 Aug 2021 | NOT 73 v GLA 76/2Match · List A | Glamorgan won by 8 wickets | Cardiff | Royal London One-Day Cup 2021 |
| 8 Aug 2021 | KEN 105 v HAM 107/4Match · List A | Hampshire won by 6 wickets (DLS method) | Beckenham | Royal London One-Day Cup 2021 |
| 8 Aug 2021 | NOR 305/6 v SOM 223Match · List A | Northamptonshire won by 81 runs (DLS method) | Northampton | Royal London One-Day Cup 2021 |
| 7 Aug 2021 | LEI 253/9 v SUR 225Match · List A | Leicestershire won by 1 run (DLS method) | Leicester | Royal London One-Day Cup 2021 |
| 6 Aug 2021 | HAM 204/8 v GLO 205/3Match · List A | Gloucestershire won by 7 wickets | Bristol | Royal London One-Day Cup 2021 |
| 6 Aug 2021 | KEN 217/9 v MID 196Match · List A | Kent won by 21 runs | Radlett | Royal London One-Day Cup 2021 |
| 6 Aug 2021 | WAR 278/6 v NOR 144/9Match · List A | Warwickshire won by 134 runs | Birmingham | Royal London One-Day Cup 2021 |
| 6 Aug 2021 | WOR 233/9 v SUS 234/8Match · List A | Sussex won by 2 wickets | Worcester | Royal London One-Day Cup 2021 |
| 6 Aug 2021 | NOT 185/5 v YORMatch · List A | No result | York | Royal London One-Day Cup 2021 |
| 5 Aug 2021 | DUR 327/6 v LAN 240Match · List A | Durham won by 87 runs | Gosforth | Royal London One-Day Cup 2021 |
| 5 Aug 2021 | GLA 277/8 v LEI 0/0Match · List A | No result | Leicester | Royal London One-Day Cup 2021 |
| 5 Aug 2021 | SOM 220 v SUR 66/0Match · List A | No result | London | Royal London One-Day Cup 2021 |
| 4 Aug 2021 | WOR 176 v HAM 180/4Match · List A | Hampshire won by 6 wickets | Southampton | Royal London One-Day Cup 2021 |
| 4 Aug 2021 | DER 258/6 v NOT 217Match · List A | Derbyshire won by 41 runs | Derby | Royal London One-Day Cup 2021 |
| 3 Aug 2021 | SUR 132 v GLA 133/5Match · List A | Glamorgan won by 5 wickets | Cardiff | Royal London One-Day Cup 2021 |
| 3 Aug 2021 | GLO 204 v ESS 207/8Match · List A | Essex won by 2 wickets | Bristol | Royal London One-Day Cup 2021 |
| 3 Aug 2021 | MID 257 v LAN 251/9Match · List A | Middlesex won by 6 runs | Manchester | Royal London One-Day Cup 2021 |
| 3 Aug 2021 | YOR 320/7 v WAR 281Match · List A | Yorkshire won by 39 runs | York | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | KEN 158 v ESS 159/1Match · List A | Essex won by 9 wickets | Chelmsford | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | HAM 162 v LAN 115/2Match · List A | Lancashire won by 51 runs (DLS method) | Southampton | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | DER 177/9 v NOR 183/2Match · List A | Northamptonshire won by 8 wickets | Northampton | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | LEI 144 v NOT 145/3Match · List A | Nottinghamshire won by 7 wickets | Welbeck | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | YOR 158/5 v SOM 159/5Match · List A | Somerset won by 5 wickets | Taunton | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | GLO 218/8 v SUS 214Match · List A | Gloucestershire won by 3 runs (DLS method) | Brighton | Royal London One-Day Cup 2021 |
| 1 Aug 2021 | MID 302/5 v WOR 289/7Match · List A | Middlesex won by 13 runs | Worcester | Royal London One-Day Cup 2021 |
| 30 Jul 2021 | NOT 92/2 v SOMMatch · List A | No result | Welbeck | Royal London One-Day Cup 2021 |
| 30 Jul 2021 | NOR 31/1 v SURMatch · List A | No result | London | Royal London One-Day Cup 2021 |
| 30 Jul 2021 | SUS 209/7 v KEN 50/1Match · List A | No result | Brighton | Royal London One-Day Cup 2021 |
| 29 Jul 2021 | DUR 335/4 v GLO 336/6Match · List A | Gloucestershire won by 4 wickets | Scarborough | Royal London One-Day Cup 2021 |
| 29 Jul 2021 | WOR 338/7 v ESS 156Match · List A | Worcestershire won by 182 runs | Chelmsford | Royal London One-Day Cup 2021 |
