| 11 Jun 2022 | SES 104/8 v CS 105/8Semi-Final · T20 | Central Sparks won by 2 wickets | Northampton | Charlotte Edwards Cup 2022 |
| 11 Jun 2022 | CS 109/8 v SV 110/4Final · T20 | Southern Vipers won by 6 wickets | Northampton | Charlotte Edwards Cup 2022 |
| 5 Jun 2022 | SES 183/9 v SUN 127Match · T20 | South East Stars won by 56 runs | Guildford | Charlotte Edwards Cup 2022 |
| 4 Jun 2022 | ND 141/4 v SV 144/4Match · T20 | Southern Vipers won by 6 wickets | Southampton | Charlotte Edwards Cup 2022 |
| 4 Jun 2022 | CS 134/4 v WS 135/3Match · T20 | Western Storm won by 7 wickets | Worcester | Charlotte Edwards Cup 2022 |
| 3 Jun 2022 | LIG 103 v THU 104/5Match · T20 | Thunder won by 5 wickets | Manchester | Charlotte Edwards Cup 2022 |
| 1 Jun 2022 | WS 109/8 v SES 112/7Match · T20 | South East Stars won by 3 wickets | Bristol | Charlotte Edwards Cup 2022 |
| 1 Jun 2022 | CS 146/5 v SUN 143/6Match · T20 | Central Sparks won by 3 runs | Northampton | Charlotte Edwards Cup 2022 |
| 1 Jun 2022 | ND 145/5 v LIG 140Match · T20 | Northern Diamonds won by 5 runs | Chester-le-Street | Charlotte Edwards Cup 2022 |
| 1 Jun 2022 | THU 94/6 v SV 97/4Match · T20 | Southern Vipers won by 6 wickets | Manchester | Charlotte Edwards Cup 2022 |
| 29 May 2022 | WS 169/5 v SUN 128/6Match · T20 | Western Storm won by 41 runs | Taunton | Charlotte Edwards Cup 2022 |
| 29 May 2022 | SES 148/6 v CS 91/7Match · T20 | South East Stars won by 10 runs (DLS method) | Birmingham | Charlotte Edwards Cup 2022 |
| 29 May 2022 | ND 124 v THU 99Match · T20 | Northern Diamonds won by 25 runs | Leeds | Charlotte Edwards Cup 2022 |
| 29 May 2022 | LIG 141 v SV 142/5Match · T20 | Southern Vipers won by 5 wickets | Nottingham | Charlotte Edwards Cup 2022 |
| 21 May 2022 | WS 145/6 v SES 148/3Match · T20 | South East Stars won by 7 wickets | Beckenham | Charlotte Edwards Cup 2022 |
| 21 May 2022 | SV 126 v ND 115/7Match · T20 | Southern Vipers won by 11 runs | Chester-le-Street | Charlotte Edwards Cup 2022 |
| 21 May 2022 | THU 152/5 v LIG 155/5Match · T20 | Lightning won by 5 wickets | Leicester | Charlotte Edwards Cup 2022 |
| 21 May 2022 | CS 153/5 v SUN 129/8Match · T20 | Central Sparks won by 24 runs | Birmingham | Charlotte Edwards Cup 2022 |
| 18 May 2022 | THU 148/7 v ND 92Match · T20 | Thunder won by 56 runs | Sale | Charlotte Edwards Cup 2022 |
| 18 May 2022 | SV 155/5 v LIG 124/8Match · T20 | Southern Vipers won by 31 runs | Southampton | Charlotte Edwards Cup 2022 |
| 18 May 2022 | CS 170/6 v SES 136Match · T20 | Central Sparks won by 34 runs | Guildford | Charlotte Edwards Cup 2022 |
| 18 May 2022 | SUN 160/5 v WS 164/9Match · T20 | Western Storm won by 1 wicket | Chelmsford | Charlotte Edwards Cup 2022 |
| 14 May 2022 | THU 102/7 v SV 103/2Match · T20 | Southern Vipers won by 8 wickets | Brighton | Charlotte Edwards Cup 2022 |
| 14 May 2022 | CS 156/4 v WS 136/6Match · T20 | Central Sparks won by 20 runs | Cardiff | Charlotte Edwards Cup 2022 |
| 14 May 2022 | SUN 122/6 v SES 123/4Match · T20 | South East Stars won by 6 wickets | Chelmsford | Charlotte Edwards Cup 2022 |
| 14 May 2022 | ND 177/5 v LIG 138/7Match · T20 | Northern Diamonds won by 39 runs | Loughborough | Charlotte Edwards Cup 2022 |
